Featured Presentation: Overcoming Scale-Up Challenges in Cell Therapy Manufacturing
- Speaker: Dan Nelson, Director Product
- Presentation Date: Wednesday, March 19, 2025
- Presentation Time: 10:00 AM
- Session Track: Cell Therapy CMC and Manufacturing
- Abstract: The presentation will address the challenges when scaling cell-based therapy production, highlighting the need for efficiency, consistency, and cost-effectiveness while preserving cell health. Throughout critical handling steps—expansion, recovery, washing, and concentration—maintaining cell viability and functionality is essential to ensure therapeutic efficacy. We will explore how shear stress, prolonged reagent exposure, and time outside controlled environments influence manufacturing strategies. By evaluating low-shear, automated processing frameworks, we demonstrate strategies to optimize cell recovery rates and minimize cell loss, supporting a streamlined approach for industrial-scale manufacturing.
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While we’re on site at Bioprocessing Europe, we’d love to connect with you! Take advantage of this opportunity to schedule a one-on-one meeting with the CARR team. Discuss your challenges, explore innovative solutions, and see how we can support your specific processing needs.
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About CARR Biosystems
CARR Biosystems is dedicated to transforming bioprocessing workflows across multiple markets, including gene therapy, cell therapy, vaccines, biologics, cellular agriculture, nucleic acids and microbial fermentation. Our innovative centrifuge solutions are engineered to deliver unmatched scalability, precision, and efficiency, empowering our partners to accelerate the development and production of life-saving therapies.
By providing advanced technologies that seamlessly transition from process development to commercial-scale manufacturing, we help our customers achieve consistent product quality, reduce operational complexities, enhance overall productivity and improved process economics. Whether supporting emerging cell-based therapies or biomolecules, CARR Biosystems stands as a trusted partner in advancing global healthcare innovation.
